QUESTION: I have been a regular blood donor since 1960.
Recently I received a letter from our local Red Cross Blood Bank informing me that I have anti-Kell antibodies and that doctors should be made aware of this if I ever need a blood transfusion.
Exactly what are anti-Kell antibodies?
ANSWER: There are many types of antigens present on red cells.
An antigen is any substance capable, under appropriate conditions, of producing a specific immune response.
Usually blood is typed for A, B, O and Rh-D antigens during a normal test, but the other antigens, including Kell, Duffy, Kidd (all named for their discoverers) and other Rh antigens may also produce an antibody response.
When blood containing these antibodies comes in contact with blood possessing the matching antigens, a reaction called "hemolysis" (destruction of red blood cells) may occur.
No treatment is necessary, but when continued transfusions are necessary, only blood that lacks the offending antigens should be used.
Specifically for you, you would need blood that has no Kell antigens, since your own blood now has anti-Kell antibodies.
It is nothing you should be concerned about now, but is important information for your physician should you require a transfusion.
The material contained here is "FOR INFORMATION ONLY" and should not replace the counsel and advice of your personal physician.
Promptly consulting your doctor is the best path to a quick and successful resolution of any medical problem.
